Step 1
The first visit, and the tests that follow it
Any couple, or any woman, who wants to know where they stand before anything is decided.
A conversation, an examination, a scan, and a list of tests with a reason for each. For both of you.
At a glance
- Where
- Here. Blood tests at a laboratory nearby, on the days named.
- How long
- About 40 minutes for the visit; the tests over one cycle.
- What you need first
- Nothing. Bring every old report you have.
- How many cycles
- None. This is the start.
Everything that happens later in fertility care depends on this visit being done properly, which is why it is the longest one. Nothing is decided at it. Its job is to find out what is going on, and to give you a short, specific list of tests with a reason attached to each one, so that the second visit can be about a plan and not about guesses.
Before you come
Both of you, if you can manage it. Part of the answer is often on his side and his test is the simplest one there is; a first visit with both of you in the room saves a month. If he cannot come, come alone and bring his questions, and his test can still be arranged.
Bring every report you have, from anywhere, however old: scans, blood tests, a semen analysis, an operation note, a discharge summary from a pregnancy that ended. Nothing is repeated without a reason, and the old results often answer questions that would otherwise need a new test.
There is no wrong day of the cycle for the first visit. If you can choose, the first few days after a period starts are the most useful, because some blood tests are timed to those days and the scan reads the ovaries most clearly then.
What happens in the room
The story first, and it takes a while. How long you have been trying and how; how your cycles run; previous pregnancies, for either of you, with anyone; illnesses, medicines, operations; smoking, alcohol, weight, shift work; what has already been tested and what it showed. Then his side: his health, any operations or injuries, any previous children, and whether he has been tested before.
Then an examination, and a scan of the uterus and ovaries. The scan shows the shape and lining of the uterus, whether there are fibroids, polyps or cysts, and the number of small follicles resting on each ovary, which is a picture of your egg reserve on the day. It takes a few minutes and it is not uncomfortable.
You leave with the list of tests, a reason for each, and the day of your cycle on which each is done. Not a diagnosis, because there is not one yet, and not a treatment plan, because a plan built before the tests is a guess.
The tests, and when they are done
| Test | When | What it tells |
|---|---|---|
| Hormones that drive the cycle (FSH, LH, oestradiol) | Day 2 to day 4 of a period | How hard the body is working to grow an egg |
| AMH | Any day | The size of the egg reserve, read a second way alongside the scan |
| Thyroid and prolactin | Any day | Two things that quietly stop ovulation and are easily corrected |
| Progesterone | About seven days before the next period is due | Whether an egg was released this cycle |
| Sugar, and a general blood count | Any day, fasting for the sugar | Health that affects a pregnancy, and PCOS’s metabolic side |
| Infection screen, blood group | Any day | Routine before any treatment, and useful for a pregnancy |
| Semen analysis, for him | After two to five days without ejaculation | Count, movement and shape; his whole side in one test |
| A tube test, if it is needed | The week after a period ends | Whether the tubes are open |
What an AMH does and does not tell you
AMH is a hormone made by the small resting follicles, so its level rises and falls with how many of them there are. A low result means fewer eggs to work with, which changes the timing of the steps and the advice about how long to try. A high result, in a woman with irregular periods, often goes with PCOS. What AMH does not do is predict a pregnancy. A woman with a low AMH who ovulates regularly can conceive without help; a woman with a high AMH who does not ovulate cannot until that is treated. The number is read alongside the scan, your age and your cycle, and you are told what it means for you and what it does not.
The tube test
The tubes carry the egg to meet the sperm, and a tube that is blocked cannot be seen on an ordinary scan. Where the story or the scan raises the question, a tube test is done: either an X-ray with a dye passed through the cervix, called an HSG, or a scan with a little saline passed the same way. The dye test is uncomfortable for a few minutes and is done at a radiology centre on a day soon after a period; the saline scan is gentler and is done in a scan room. Which one, and whether it is needed at all, depends on what the story and the scan have already shown. It is not done on the first visit and it is not done for everyone.
His test
A semen analysis: one sample, produced after two to five days of abstinence, read by a laboratory that does this every day, with the result back in a day or two. It is one of the most useful tests in the work-up, and often the one that is skipped, usually because nobody asked him. If a result is abnormal it is repeated after a few weeks before anything is concluded, because one sample can be wrong. Everything else on his side is on the page for him.
Before you decide
The tests answer a small number of questions: whether an egg is being released, whether the tubes are open, whether the count is adequate, and what the reserve looks like. They do not answer the question you most want answered, which is whether and when you will conceive. This clinic does not give a figure for your own case, before or after the tests. What you will be told is what each result means for you, in words, what the sensible next step is, and how long to give it. Sometimes the answer at the second visit is that nothing needs treating and the sensible step is time, with a date to come back. That is a real answer and it is given when it is true.
Questions patients ask
Do we both have to come to the first visit?
Ideally, yes. If he cannot, come alone, and his test can be arranged without a consultation.
Will I be examined?
Yes, gently, and a scan is done the same day. Nothing on the first visit is painful.
Which day of my cycle should I come?
Any day is fine. If you can choose, the first few days of a period, because two of the blood tests are timed to those days and the scan is clearest then.
We had tests last year. Will they be repeated?
Only those old enough to have changed, or unclear. Bring them all.
How long until we have all the results?
Usually one cycle, because the blood tests are spread across it. The second visit is booked for after the last result is in.
What if everything comes back normal?
Then you have good news of a kind, and a name for it: unexplained infertility. It has its own treatments, and the next step is discussed at the second visit.
Your doctor
The first visit is where I earn the right to give advice later. I ask more questions than you expect, I examine, and I order the tests that will change the plan and not the ones that will not. Then I explain what each is for. If you leave that visit understanding why every test on the list is there, the rest of the process is much less frightening.
Dr. Palaparthi Lalitha Devi
MBBS, MS (OBG), DNB.
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